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Quality Control of Custom Adenovirus Preparation
Description
In addition to the quality tests included with some of our services,
the following tests are offered to assess the infectivity, purity
and functionality of the generated recombinant Adenovirus.
In addition to providing the viral titer, Viral Particle Titration
Assays can also be used to test the quality of Adenovirus preparation
by determining the VP/IU ratio (viral particle to infectious unit
ratio).
The Identity Test consists of performing a Western Blot to confirm
the identity of a recombinant protein produced with an Adenovirus
vector.
Four or five additional tests are offered to assure the best possible
quality of the viral preparation:
- the Sterility Test confirms the sterility of the viral stock
- the Mycoplasma Test verifies the abcense of mycoplasma in the
viral preparation
- the Endotoxin Tests document the level of endotoxin in the viral
stock (gel clot on chromagenic tests available)
- the RCA-PCR Assay tests the presence of RCA (Replication Competent
Adenovirus) in the preparation
Photo to put here comes later
| Service # |
Description |
| ACS0060 |
Adenovirus Titration by Plaque Assay (PFU/mL) |
| ACS0070 |
Adenovirus Titration by TCID50 (TCID50/mL) |
| ACS0075 |
Adenovirus Titration by OD260 (VP/mL) |
| ACS0100 |
Identity Test: Western Analysis on Large Amplification Stock |
| ACS0090 |
Sterility Test |
| ACS0091 |
Mycoplasma Test |
| ACS0092 |
Endotoxin Test (by Gel Clot) |
| ACS0093 |
Endotoxin Test (Chromogenic) |
| ACS0094 |
RCA-PCR Assay |
For a complete list of MERLIN Custom Service catalog numbers, click
here.
For contact information, click
here.
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