­¦ý°±·>œ RTœQÏ€¡G ømJbjbjéé %lÏ„Ï„mF]JJJJJJJ^^^^^ j\^Ö–’’’’’’’’JLLLLLL${Ùo^pJ’’’’’pjJJ’’’jjj’¨ J’J’J^^JJJJ’JjýjJJJJ’Ä_EŠ1ìæ^^é ÐJpQBI-LTRrevBFP (5350bp) 1 CAGGTGGCAC TTTTCGGGGA AATGTGCGCG GAACCCCTAT TTGTTTATTT TTCTAAATAC ATTCAAATAT GTCCACCGTG AAAAGCCCCT TTACACGCGC CTTGGGGATA AACAAATAAA AAGATTTATG TAAGTTTATA BspMI ~~~~~ +3 MetSerIle 71 GTATCCGCTC ATGAGACAAT AACCCTGATA AATGCTTCAA TAATATTGAA AAAGGAAGAG TATGAGTATT CATAGGCGAG TACTCTGTTA TTGGGACTAT TTACGAAGTT ATTATAACTT TTTCCTTCTC ATACTCATAA +3 GlnHisPheArg ValAlaLeu IleProPhe PheAlaAlaPhe CysLeuPro ValPheAla HisProGluT 141 CAACATTTCC GTGTCGCCCT TATTCCCTTT TTTGCGGCAT TTTGCCTTCC TGTTTTTGCT CACCCAGAAA GTTGTAAAGG CACAGCGGGA ATAAGGGAAA AAACGCCGTA AAACGGAAGG ACAAAAACGA GTGGGTCTTT +3 hrLeuValLys ValLysAsp AlaGluAspGln LeuGlyAla ArgValGly TyrIleGluLeu AspLeuAs 211 CGCTGGTGAA AGTAAAAGAT GCTGAAGATC AGTTGGGTGC ACGAGTGGGT TACATCGAAC TGGATCTCAA GCGACCACTT TCATTTTCTA CGACTTCTAG TCAACCCACG TGCTCACCCA ATGTAGCTTG ACCTAGAGTT +3 nSerGlyLys IleLeuGluSer PheArgPro GluGluArg PheProMetMet SerThrPhe LysValLeu 281 CAGCGGTAAG ATCCTTGAGA GTTTTCGCCC CGAAGAACGT TTTCCAATGA TGAGCACTTT TAAAGTTCTG GTCGCCATTC TAGGAACTCT CAAAAGCGGG GCTTCTTGCA AAAGGTTACT ACTCGTGAAA ATTTCAAGAC +3 LeuCysGlyAla ValLeuSer ArgIleAsp AlaGlyGlnGlu GlnLeuGly ArgArgIle HisTyrSerG 351 CTATGTGGCG CGGTATTATC CCGTATTGAC GCCGGGCAAG AGCAACTCGG TCGCCGCATA CACTATTCTC GATACACCGC GCCATAATAG GGCATAACTG CGGCCCGTTC TCGTTGAGCC AGCGGCGTAT GTGATAAGAG +3 lnAsnAspLeu ValGluTyr SerProValThr GluLysHis LeuThrAsp GlyMetThrVal ArgGluLe 421 AGAATGACTT GGTTGAGTAC TCACCAGTCA CAGAAAAGCA TCTTACGGAT GGCATGACAG TAAGAGAATT TCTTACTGAA CCAACTCATG AGTGGTCAGT GTCTTTTCGT AGAATGCCTA CCGTACTGTC ATTCTCTTAA +3 uCysSerAla AlaIleSerMet SerAspAsn ThrAlaAla AsnLeuLeuLeu ThrThrIle GlyGlyPro 491 ATGCAGTGCT GCCATAAGCA TGAGTGATAA CACTGCGGCC AACTTACTTC TGACAACGAT CGGAGGACCG TACGTCACGA CGGTATTCGT ACTCACTATT GTGACGCCGG TTGAATGAAG ACTGTTGCTA GCCTCCTGGC +3 LysGluLeuThr AlaPhePhe HisAsnMet GlyAspHisVal ThrArgLeu AspArgTrp GluProGluL 561 AAGGAGCTAA CCGCTTTTTT TCACAACATG GGGGATCATG TAACTCGCCT TGATCGTTGG GAACCGGAGC TTCCTCGATT GGCGAAAAAA AGTGTTGTAC CCCCTAGTAC ATTGAGCGGA ACTAGCAACC CTTGGCCTCG +3 euAsnGluAla IleProAsn AspGluArgAsp ThrThrMet ProValAla MetAlaThrThr LeuArgLy 631 TGAATGAAGC CATACCAAAC GACGAGCGTG ACACCACGAT GCCTGTAGCA ATGGCAACAA CGTTGCGCAA ACTTACTTCG GTATGGTTTG CTGCTCGCAC TGTGGTGCTA CGGACATCGT TACCGTTGTT GCAACGCGTT +3 sLeuLeuThr GlyGluLeuLeu ThrLeuAla SerArgGln GlnLeuIleAsp TrpMetGlu AlaAspLys 701 ACTATTAACT GGCGAACTAC TTACTCTAGC TTCCCGGCAA CAATTAATAG ACTGGATGGA GGCGGATAAA TGATAATTGA CCGCTTGATG AATGAGATCG AAGGGCCGTT GTTAATTATC TGACCTACCT CCGCCTATTT +3 ValAlaGlyPro LeuLeuArg SerAlaLeu ProAlaGlyTrp PheIleAla AspLysSer GlyAlaGlyG 771 GTTGCAGGAC CACTTCTGCG CTCGGCCCTT CCGGCTGGCT GGTTTATTGC TGATAAATCT GGAGCCGGTG CAACGTCCTG GTGAAGACGC GAGCCGGGAA GGCCGACCGA CCAAATAACG ACTATTTAGA CCTCGGCCAC +3 luArgGlySer ArgGlyIle IleAlaAlaLeu GlyProAsp GlyLysPro SerArgIleVal ValIleTy 841 AGCGTGGGTC TCGCGGTATC ATTGCAGCAC TGGGGCCAGA TGGTAAGCCC TCCCGTATCG TAGTTATCTA TCGCACCCAG AGCGCCATAG TAACGTCGTG ACCCCGGTCT ACCATTCGGG AGGGCATAGC ATCAATAGAT +3 rThrThrGly SerGlnAlaThr MetAspGlu ArgAsnArg GlnIleAlaGlu IleGlyAla SerLeuIle 911 CACGACGGGC AGTCAGGCAA CTATGGATGA ACGAAATAGA CAGATCGCTG AGATAGGTGC CTCACTGATT GTGCTGCCCG TCAGTCCGTT GATACCTACT TGCTTTATCT GTCTAGCGAC TCTATCCACG GAGTGACTAA +3 LysHisTrp*** 981 AAGCATTGGT AACTGTCAGA CCAAGTTTAC TCATATATAC TTTAGATTGA TTTAAAACTT CATTTTTAAT TTCGTAACCA TTGACAGTCT GGTTCAAATG AGTATATATG AAATCTAACT AAATTTTGAA GTAAAAATTA 1051 TTAAAAGGAT CTAGGTGAAG ATCCTTTTTG ATAATCTCAT GACCAAAATC CCTTAACGTG AGTTTTCGTT AATTTTCCTA GATCCACTTC TAGGAAAAAC TATTAGAGTA CTGGTTTTAG GGAATTGCAC TCAAAAGCAA 1121 CCACTGAGCG TCAGACCCCG TAGAAAAGAT CAAAGGATCT TCTTGAGATC CTTTTTTTCT GCGCGTAATC GGTGACTCGC AGTCTGGGGC ATCTTTTCTA GTTTCCTAGA AGAACTCTAG GAAAAAAAGA CGCGCATTAG 1191 TGCTGCTTGC AAACAAAAAA ACCACCGCTA CCAGCGGTGG TTTGTTTGCC GGATCAAGAG CTACCAACTC ACGACGAACG TTTGTTTTTT TGGTGGCGAT GGTCGCCACC AAACAAACGG CCTAGTTCTC GATGGTTGAG 1261 TTTTTCCGAA GGTAACTGGC TTCAGCAGAG CGCAGATACC AAATACTGTC CTTCTAGTGT AGCCGTAGTT AAAAAGGCTT CCATTGACCG AAGTCGTCTC GCGTCTATGG TTTATGACAG GAAGATCACA TCGGCATCAA 1331 AGGCCACCAC TTCAAGAACT CTGTAGCACC GCCTACATAC CTCGCTCTGC TAATCCTGTT ACCAGTGGCT TCCGGTGGTG AAGTTCTTGA GACATCGTGG CGGATGTATG GAGCGAGACG ATTAGGACAA TGGTCACCGA 1401 GCTGCCAGTG GCGATAAGTC GTGTCTTACC GGGTTGGACT CAAGACGATA GTTACCGGAT AAGGCGCAGC CGACGGTCAC CGCTATTCAG CACAGAATGG CCCAACCTGA GTTCTGCTAT CAATGGCCTA TTCCGCGTCG 1471 GGTCGGGCTG AACGGGGGGT TCGTGCACAC AGCCCAGCTT GGAGCGAACG ACCTACACCG AACTGAGATA CCAGCCCGAC TTGCCCCCCA AGCACGTGTG TCGGGTCGAA CCTCGCTTGC TGGATGTGGC TTGACTCTAT 1541 CCTACAGCGT GAGCATTGAG AAAGCGCCAC GCTTCCCGAA GGGAGAAAGG CGGACAGGTA TCCGGTAAGC GGATGTCGCA CTCGTAACTC TTTCGCGGTG CGAAGGGCTT CCCTCTTTCC GCCTGTCCAT AGGCCATTCG 1611 GGCAGGGTCG GAACAGGAGA GCGCACGAGG GAGCTTCCAG GGGGGAACGC CTGGTATCTT TATAGTCCTG CCGTCCCAGC CTTGTCCTCT CGCGTGCTCC CTCGAAGGTC CCCCCTTGCG GACCATAGAA ATATCAGGAC 1681 TCGGGTTTCG CCACCTCTGA CTTGAGCGTC GATTTTTGTG ATGCTCGTCA GGGGGGCCGA GCCTATGGAA AGCCCAAAGC GGTGGAGACT GAACTCGCAG CTAAAAACAC TACGAGCAGT CCCCCCGGCT CGGATACCTT 1751 AAACGCCAGC AACGCGGCCT TTTTACGGTT CCTGGCCTTT TGCTGGCCTT TTGCTCACAT GTTCTTTCCT TTTGCGGTCG TTGCGCCGGA AAAATGCCAA GGACCGGAAA ACGACCGGAA AACGAGTGTA CAAGAAAGGA 1821 GCGTTATCCC CTGATTCTGT GGATAACCGT ATTACCGCCT TTGAGTGAGC TGATACCGCT CGCCGCAGCC CGCAATAGGG GACTAAGACA CCTATTGGCA TAATGGCGGA AACTCACTCG ACTATGGCGA GCGGCGTCGG 1891 GAACGACCGA GCGCAGCGAG TCAGTGAGCG AGGAAGCGGA AGAGCGCCCA ATACGCAAAC CGCCTCTCCC CTTGCTGGCT CGCGTCGCTC AGTCACTCGC TCCTTCGCCT TCTCGCGGGT TATGCGTTTG GCGGAGAGGG 1961 CGCGCGTTGG CCGATTCATT AATGCAGCTG GCACGACAGG TTTCCCGACT GGAAAGCGGG CAGTGAGCGC GCGCGCAACC GGCTAAGTAA TTACGTCGAC CGTGCTGTCC AAAGGGCTGA CCTTTCGCCC GTCACTCGCG 2031 AACGCAATTA ATGTGAGTTA CCTCACTCAT TAGGCACCCC AGGCTTTACA CTTTATGCTT CCGGCTCCTA TTGCGTTAAT TACACTCAAT GGAGTGAGTA ATCCGTGGGG TCCGAAATGT GAAATACGAA GGCCGAGGAT 2101 TGTTGTGTGG AATTGTGAGC GGATAACAAT TTCACACAGG AAACAGCTAT GACCATGATT ACGCCAAGCT ACAACACACC TTAACACTCG CCTATTGTTA AAGTGTGTCC TTTGTCGATA CTGGTACTAA TGCGGTTCGA EcoNI ~~~~~~~~~~~~ 2171 CGGAATTAAC CCTCACTAAA GGGAACAAAA GCTGGCGCTC TCCCTTATGC GACTCCTGCA TTAGGAAGCA GCCTTAATTG GGAGTGATTT CCCTTGTTTT CGACCGCGAG AGGGAATACG CTGAGGACGT AATCCTTCGT 2241 GCCCAGTAGT AGGTTGAGGC CGTTGAGCAC CGCCGCCGCA AGGAATGGTG CTTTAAGACC AATGACTTAC CGGGTCATCA TCCAACTCCG GCAACTCGTG GCGGCGGCGT TCCTTACCAC GAAATTCTGG TTACTGAATG BglII ~~~~~~ 2311 AAGGCAGCTG TAGATCTTAG CCACTTTTTA AAAGAAAAGG GGGGACTGGA AGGGCTAATT CACTCCCAAA TTCCGTCGAC ATCTAGAATC GGTGAAAAAT TTTCTTTTCC CCCCTGACCT TCCCGATTAA GTGAGGGTTT 2381 GAAGACAAGA TATCCTTGAT CTGTGGATCT ACCACACACA AGGCTACTTC CCTGATTGAC AGAACTACAC CTTCTGTTCT ATAGGAACTA GACACCTAGA TGGTGTGTGT TCCGATGAAG GGACTAACTG TCTTGATGTG 2451 ACCAGGGCCA GGGGTCAGAT ATCCACTGAC CTTTGGATGG TGCTACAAGC TAGTACCAGT TGAGCCAGAT TGGTCCCGGT CCCCAGTCTA TAGGTGACTG GAAACCTACC ACGATGTTCG ATCATGGTCA ACTCGGTCTA 2521 AAGATAGAAG AGGCCAATAA AGGAGAGAAC ACCAGCTTGT TACACCCTGT GAGCCTGCAT GGGATGGATG TTCTATCTTC TCCGGTTATT TCCTCTCTTG TGGTCGAACA ATGTGGGACA CTCGGACGTA CCCTACCTAC 2591 ACCCGGAGAG AGAAGTGTTA GAGTGGAGGT TTGACAGCCG CCTAGCATTT CATCACGTGG CCCGAGAGCT TGGGCCTCTC TCTTCACAAT CTCACCTCCA AACTGTCGGC GGATCGTAAA GTAGTGCACC GGGCTCTCGA 2661 GCATCCGGAG TACTTCAAGA ACTGCTGACA TCGAGCTTGC TACAAGGGAC TTTCCGCTGG GGACTTTCCA CGTAGGCCTC ATGAAGTTCT TGACGACTGT AGCTCGAACG ATGTTCCCTG AAAGGCGACC CCTGAAAGGT 2731 GGGAGGCGTG GCCTGGGCGG GACTGGGGAG TGGCGAGCCC TCAGATCCTG CATATAAGCA GCTGCTTTTT CCCTCCGCAC CGGACCCGCC CTGACCCCTC ACCGCTCGGG AGTCTAGGAC GTATATTCGT CGACGAAAAA BglII ~~~~~~~ 2801 GCCTGTACTG GGTCTCTCTG GTTAGACCAG ATCTGAGCCT GGGAGCTCTC TGGCTAACTA GGGAACCCAC CGGACATGAC CCAGAGAGAC CAATCTGGTC TAGACTCGGA CCCTCGAGAG ACCGATTGAT CCCTTGGGTG +1 MetAlaGly ArgSerGly AspSerAspGlu GluLeuIle ArgThrVal AflII ~~~~~~ 2871 TGCTTAAGCC TCAATAAAGC TCATGGCAGG AAGAAGCGGA GACAGCGACG AAGAGCTCAT CAGAACAGTC ACGAATTCGG AGTTATTTCG AGTACCGTCC TTCTTCGCCT CTGTCGCTGC TTCTCGAGTA GTCTTGTCAG +1 ArgLeuIleLys LeuLeuTyr GlnSerAsn ProProProAsn ProGluGly ThrArgGln AlaArgArgA 2941 AGACTGATCA AGCTTCTCTA TCAAAGCAAC CCACCTCCCA ATCCCGAGGG GACGCGTCAG GCGCGCAGGA TCTGACTAGT TCGAAGAGAT AGTTTCGTTG GGTGGAGGGT TAGGGCTCCC CTGCGCAGTC CGCGCGTCCT +1 snArgArgArg ArgTrpArg GluArgGlnArg GlnIleHis SerIleSer GluArgIleLeu GlyThrTy 3011 ATAGAAGGCG CCGGTGGAGA GAGAGACAGA GACAGATCCA TTCGATATCT GAACGGATCC TTGGCACTTA TATCTTCCGC GGCCACCTCT CTCTCTGTCT CTGTCTAGGT AAGCTATAGA CTTGCCTAGG AACCGTGAAT +1 rLeuGlyArg SerAlaGluPro ValProLeu GlnLeuPro ProLeuGluArg LeuThrLeu AspCysAsn 3081 TCTGGGACGA TCTGCAGAGC CTGTGCCTCT TCAGCTACCA CCGCTTGAGA GGTTAACTCT TGATTGTAAC AGACCCTGCT AGACGTCTCG GACACGGAGA AGTCGATGGT GGCGAACTCT CCAATTGAGA ACTAACATTG +1 GluAspCysGly ThrSerGly ThrGlnGly ValGlySerPro GlnIleLeu ValGluSer ProThrValL 3151 GAGGATTGTG GAACTAGTGG GACACAGGGT GTGGGGTCAC CTCAAATATT GGTGGAATCT CCTACAGTAC CTCCTAACAC CTTGATCACC CTGTGTCCCA CACCCCAGTG GAGTTTATAA CCACCTTAGA GGATGTCATG +1 euAspAlaGln GluMetAla SerLysGlyGlu GluLeuPhe ThrGlyVal ValProIleLeu ValGluLe NheI ~~~~~~~ 3221 TCGACGCGCA AGAAATGGCT AGCAAAGGAG AAGAACTCTT CACTGGAGTT GTCCCAATTC TTGTTGAATT AGCTGCGCGT TCTTTACCGA TCGTTTCCTC TTCTTGAGAA GTGACCTCAA CAGGGTTAAG AACAACTTAA +1 uAspGlyAsp ValAsnGlyHis LysPheSer ValSerGly GluGlyGluGly AspAlaThr TyrGlyLys 3291 AGATGGTGAT GTTAACGGCC ACAAGTTCTC TGTCAGTGGA GAGGGTGAAG GTGATGCAAC ATACGGAAAA TCTACCACTA CAATTGCCGG TGTTCAAGAG ACAGTCACCT CTCCCACTTC CACTACGTTG TATGCCTTTT +1 LeuThrLeuLys PheIleCys ThrThrGly LysLeuProVal ProTrpPro ThrLeuVal ThrThrLeuS 3361 CTTACCCTGA AGTTCATCTG CACTACTGGC AAACTGCCTG TTCCATGGCC AACACTAGTC ACTACTCTCT GAATGGGACT TCAAGTAGAC GTGATGACCG TTTGACGGAC AAGGTACCGG TTGTGATCAG TGATGAGAGA +1 erHisGlyVal GlnCysPhe SerArgTyrPro AspHisMet LysArgHis AspPhePheLys SerAlaMe 3431 CTCATGGTGT TCAATGCTTT TCAAGATACC CGGATCATAT GAAACGGCAT GACTTTTTCA AGAGTGCCAT GAGTACCACA AGTTACGAAA AGTTCTATGG GCCTAGTATA CTTTGCCGTA CTGAAAAAGT TCTCACGGTA +1 tProGluGly TyrValGlnGlu ArgThrIle PhePheLys AspAspGlyAsn TyrLysThr ArgAlaGlu 3501 GCCCGAAGGT TATGTACAGG AAAGGACCAT CTTCTTCAAA GATGACGGCA ACTACAAGAC ACGTGCTGAA CGGGCTTCCA ATACATGTCC TTTCCTGGTA GAAGAAGTTT CTACTGCCGT TGATGTTCTG TGCACGACTT +1 ValLysPheGlu GlyAspThr LeuValAsn ArgIleGluLeu LysGlyIle AspPheLys GluAspGlyA 3571 GTCAAGTTTG AAGGTGATAC CCTTGTTAAT AGAATCGAGT TAAAAGGTAT TGATTTTAAA GAAGATGGAA CAGTTCAAAC TTCCACTATG GGAACAATTA TCTTAGCTCA ATTTTCCATA ACTAAAATTT CTTCTACCTT +1 snIleLeuGly HisLysLeu GluTyrAsnTyr AsnSerHis AsnValTyr IleMetAlaAsp LysGlnLy 3641 ACATTCTTGG ACACAAATTG GAATACAACT ATAACTCACA CAATGTATAC ATCATGGCAG ACAAACAAAA TGTAAGAACC TGTGTTTAAC CTTATGTTGA TATTGAGTGT GTTACATATG TAGTACCGTC TGTTTGTTTT +1 sAsnGlyIle LysAlaAsnPhe LysIleArg HisAsnIle GluAspGlySer ValGlnLeu AlaAspHis 3711 GAATGGAATC AAAGCGAACT TCAAGATCCG CCACAACATT GAAGATGGAA GCGTTCAACT AGCAGACCAT CTTACCTTAG TTTCGCTTGA AGTTCTAGGC GGTGTTGTAA CTTCTACCTT CGCAAGTTGA TCGTCTGGTA +1 TyrGlnGlnAsn ThrProIle GlyAspGly ProValLeuLeu ProAspAsn HisTyrLeu SerThrGlnS 3781 TATCAACAAA ATACTCCAAT TGGCGATGGC CCTGTCCTTT TACCAGACAA CCATTACCTG TCCACACAAT ATAGTTGTTT TATGAGGTTA ACCGCTACCG GGACAGGAAA ATGGTCTGTT GGTAATGGAC AGGTGTGTTA +1 erAlaLeuSer LysAspPro AsnGluLysArg AspHisMet ValLeuLeu GluPheValThr AlaAlaGl 3851 CTGCCCTTTC GAAAGATCCC AACGAAAAGA GAGACCACAT GGTCCTTCTT GAGTTTGTAA CAGCTGCTGG GACGGGAAAG CTTTCTAGGG TTGCTTTTCT CTCTGGTGTA CCAGGAAGAA CTCAAACATT GTCGACGACC +1 yIleThrHis GlyMetAspGlu LeuTyrLys *** XhoI ~~~~~~~ 3921 GATTACACAT GGCATGGATG AACTATACAA ATAAGGATCT CGAGTCAGGA ACTAAAGAGA ATTGACTCTA CTAATGTGTA CCGTACCTAC TTGATATGTT TATTCCTAGA GCTCAGTCCT TGATTTCTCT TAACTGAGAT XmaI ~~~~~~~ 3991 GAGGATCCCG GGGCGAGCTC GAATTCGATC CAGACATGAT AAGATACATT GATGAGTTTG GACAAACCAC CTCCTAGGGC CCCGCTCGAG CTTAAGCTAG GTCTGTACTA TTCTATGTAA CTACTCAAAC CTGTTTGGTG 4061 AACTAGAATG CAGTGAAAAA AATGCTTTAT TTGTGAAATT TGTGATGCTA TTGCTTTATT TGTAACCATT TTGATCTTAC GTCACTTTTT TTACGAAATA AACACTTTAA ACACTACGAT AACGAAATAA ACATTGGTAA 4131 ATAAGCTGCA ATAAACAAGT TAACAACAAC AATTGCATTC ATTTTATGTT TCAGGTTCAG GGGGAGGTGT TATTCGACGT TATTTGTTCA ATTGTTGTTG TTAACGTAAG TAAAATACAA AGTCCAAGTC CCCCTCCACA 4201 GGGAGGTTTT TTAAAGCAAG TAAAACCTCT ACAAATGTGG TATGGCTGAT TATGATCGAA TTCTTGAAGA CCCTCCAAAA AATTTCGTTC ATTTTGGAGA TGTTTACACC ATACCGACTA ATACTAGCTT AAGAACTTCT 4271 CGAAAGGGCC TCGTGATACG CCTATTTTTA TAGGTTAATG TCATGATAAT AATGGTTTCT TAGACGTCAG GCTTTCCCGG AGCACTATGC GGATAAAAAT ATCCAATTAC AGTACTATTA TTACCAAAGA ATCTGCAGTC 4341 GTGGCACTTT TCGGGGAAAT GTGCGCGGAA CCCCTATTTG TTTATTTTTC TAAATACATT CAAATATGTA CACCGTGAAA AGCCCCTTTA CACGCGCCTT GGGGATAAAC AAATAAAAAG ATTTATGTAA GTTTATACAT 4411 TCCGCTCATG AGACAATAAC CCTGATAAAT GCTTCAATAA TATTGAAAAA GGAAGAGTAT GAGTATTCAA AGGCGAGTAC TCTGTTATTG GGACTATTTA CGAAGTTATT ATAACTTTTT CCTTCTCATA CTCATAAGTT 4481 CATTTCCGTG TCGCCCTTAT TCCCTTTTTT GCGGCATTTT GCCTTCCTGT TTTTGCTCAC CCAGAAACGC GTAAAGGCAC AGCGGGAATA AGGGAAAAAA CGCCGTAAAA CGGAAGGACA AAAACGAGTG GGTCTTTGCG 4551 TGGTGAAAGT AAAAGATGCT GAAGATCAGT TGGGTGCACG AGTGGGTTAC ATCGAACTGG ATCTCAACAG ACCACTTTCA TTTTCTACGA CTTCTAGTCA ACCCACGTGC TCACCCAATG TAGCTTGACC TAGAGTTGTC NotI SacII ~~~~~~~~~ ~~~ 4621 CGGTAAGATC CTTGAGAGTT TTCGCCCCGA AGAACGGGGG GATCCACTAG TTCTAGAGCG GCCGCCACCG GCCATTCTAG GAACTCTCAA AAGCGGGGCT TCTTGCCCCC CTAGGTGATC AAGATCTCGC CGGCGGTGGC SacII ~~~ 4691 CGGTGGAGCT CCAATTCGCC CTATAGTGAG TCGTATTACA ATTCACTGGC CGTCGTTTTA CAACGTCGTG GCCACCTCGA GGTTAAGCGG GATATCACTC AGCATAATGT TAAGTGACCG GCAGCAAAAT GTTGCAGCAC 4761 ACTGGGAAAA CCCTGGCGTT ACCCAACTTA ATCGCCTTGC AGCACATCCC CCCTTCGCCA GCTGGCGTAA TGACCCTTTT GGGACCGCAA TGGGTTGAAT TAGCGGAACG TCGTGTAGGG GGGAAGCGGT CGACCGCATT 4831 TAGCGAAGAG GCCCGCACCG ATCGCCCTTC CCAACAGTTG CGTAGCCTGA ATGGCGAATG GGACGCGCCC ATCGCTTCTC CGGGCGTGGC TAGCGGGAAG GGTTGTCAAC GCATCGGACT TACCGCTTAC CCTGCGCGGG 4901 TGTAGCGGCG CATTAAGCGC GGCGGGTGTG GTGGTTACGC GCAGCGTGAC CGCTACACTT GCCAGCGCCC ACATCGCCGC GTAATTCGCG CCGCCCACAC CACCAATGCG CGTCGCACTG GCGATGTGAA CGGTCGCGGG 4971 TAGCGCCCGC TCCTTTCGCT TTCTTCCCTT CCTTTCTCGC CACGTTCGCC GGCTTTCCCC GTCAAGCTCT ATCGCGGGCG AGGAAAGCGA AAGAAGGGAA GGAAAGAGCG GTGCAAGCGG CCGAAAGGGG CAGTTCGAGA 5041 AAATCGGGGG CTCCCTTTAG GGTTCCGATT TAGTGCTTTA CGGCACCTCG ACCCCAAAAA ACTTGATTAG TTTAGCCCCC GAGGGAAATC CCAAGGCTAA ATCACGAAAT GCCGTGGAGC TGGGGTTTTT TGAACTAATC 5111 GGTGATGGTT CACGTAGTGG GCCATCGCCC TGATAGACGG TTTTTCGCCC TTTGACGTTG GAGTCCACGT CCACTACCAA GTGCATCACC CGGTAGCGGG ACTATCTGCC AAAAAGCGGG AAACTGCAAC CTCAGGTGCA 5181 TCTTTAATAG TGGACTCTTG TTCCAAACTG GAACAACACT CAACCCTATC TCGGTCTATT CTTTTGATTT AGAAATTATC ACCTGAGAAC AAGGTTTGAC CTTGTTGTGA GTTGGGATAG AGCCAGATAA GAAAACTAAA 5251 ATAAGGGATT TTGCCGATTT CGGCCTATTG GTTAAAAAAT GAGCTGATTT AACAAAAATT TAACGCGAAT TATTCCCTAA AACGGCTAAA GCCGGATAAC CAATTTTTTA CTCGACTAAA TTGTTTTTAA ATTGCGCTTA 5321 TTTAACAAAA TATTAACGTT TACAATTTGG AAATTGTTTT ATAATTGCAA ATGTTAAACC BspMI ~ lJmJšÙÒCJ CJOJQJ5ÅCJqŠ!yz‹)ÅÇ1âä·9ëíÈA ô ö Ò I ° ¢ ÏÏÏÏÏÏÏÏÏÏÏÏÏÏÏÏÏÏÏÏÏÏÏÏÏÏÏd• h­8Ýpÿ @ qŠ!yz‹)ÅÇ1âä·9ëíÈA ô ö Ò I ° ¢ ˜ Q ©  Y ± ¾ a ¼ † i¡¬qŠ !y‹³)ÅŽ1â·’9ëÈÍBöõÛKL§¸›U‚Æ^_…h¿¡qr "#{²Œ,ÑÖð56霜œœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœœ d¢ ˜ Q ©  Y 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