 HER-2/neu Probe
N-myc Probe
(MYCN) Probe
| HER-2/neu Probe (ERBB2) |
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Alterations
of the HER-2/neu proto-oncogene have been implicated in the carcinogenesis
and prognosis of breast cancer. The HER-2/neu (also called ERBB2) gene
encodes a 185 kDa transmembrane cell surface glycoprotein and is a member
of the tyrosine kinase family with a high degree of homology to the epidermal
growth factor (EGF-R). Amplification of HER-2/neu has also been reported
in prostate carcinoma, uterus endometrial cancer and primary gastric cancer.
The new developed
Qbiogene probe for HER-2/neu, labeled with Rhodamine (red), uses the Universal Linkage System (ULS®)
and is optimized to detect amplification of the HER-2/neu gene region.
The included Chromosome 17 Alpha-Satellite probe, labeled with FITC (green), serves as internal control
and simultaneously defines the ploidy status of Chromosome 17.
Localization: Locus: 17q11.2 – q12, Gene: HER-2/neu (ERBB2), Probe
Size : 450 kb
Ordering Information
| RFONC1712 |
HER-2/neu / Alphasat.17 |
Dual-Color |
10 |
Related Product
RFONCHER2 Probe and reagents for 50 HER-2/neu assays
Description
of the HER-2/neu probe in PDF format - Click here
Ordering Information
| RFONC0224 |
N-myc /
Alphasat. 2 |
Dual-Color |
10 |
Related Probe
PONC0136 1p36
probe |
|
Description of the N-myc/Alphasat. 2 probe cocktail and the 1p36 probe
in PDF format - Click here
|
