Dimethyl Sulfoxide (DMSO), cell culture reagent (CAS 67-68-5) | SC-358801

Dimethyl Sulfoxide (DMSO), cell culture reagent, is a high-purity polar aprotic solvent widely used in cell culture, molecular biology, and biochemical research. It is particularly valued for its role in cryopreservation, where it acts as an effective cryoprotectant by reducing ice crystal formation and preserving cell viability during freezing and thawing processes.

DMSO exhibits exceptional solvating properties, enabling the dissolution of a wide range of highly polar and hydrophobic compounds, including small biomolecules containing multiple protic functional groups. This makes it an essential reagent for preparing stock solutions in biological and pharmaceutical research.

In molecular biology applications, DMSO is commonly used as a PCR additive, where it enhances amplification efficiency by inhibiting the formation of secondary structures in GC-rich DNA fragments. Its presence improves template denaturation, leading to increased PCR yield and specificity.

Additionally, DMSO is employed as a reaction solvent and oxidation reagent in various chemical transformations, further highlighting its versatility in both chemical synthesis and life science research.

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